The Effect of Honey Consumption Compared with Sucrose on Blood Pressure and Fasting Blood Glucose in Healthy Young Subjects

Hamid Rasad, Arash Dashtabi, Marzieh Khansari, Fakhredin Chaboksavar, Naseh Pahlavani, Zahra Maghsoudi, Mohammad Hassan Entezari


Background: Several studies have shown that honey consumption can have beneficial effects on cardiovascular disease indicators. This study aimed to assess the effect of honey consumption compared with sucrose on fasting blood glucose and blood pressure among young healthy subjects.

Methods: Sixty healthy subjects, aged 18 to 30 years, enrolled to this double blind randomized trial for one month. Participants assigned randomly to honey (received 70 gram honey per day) and sucrose (received 70 gram sucrose per day) groups. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured and fasting blood sugar was collected from all participants in the beginning and end of study.

Results:  In this trial, the baseline FBS, SBP and DBP were not different between honey and sucrose groups (P > 0.3). We found that consumption of honey can decrease the FBS in healthy young subjects, but intake of sucrose increase it. Moreover, reduction of the FBS in honey group was significant than sucrose group (P < 0.001). Honey and sucrose consumption cannot decrease the SBP and DBP, significantly (P > 0.4). In all of these analyses, confounding variable including age, physical activity and some nutrient intake were adjusted.

Conclusion: Honey consumption can decrease the FBS, but has no effect on SBP and DBP. Further studies are needed to confirm our findings.

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Gordon DJ, Probstfield JL, Garrison RJ, Neaton JD, Castelli WP, Knoke JD, et al (1989). High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulatio.;79(1):8-15.

Musselman DL, Evans DL, Nemeroff CB.(1998) The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Arch Gen Psychiatry;55(7):580-92.

Foley RN, Parfrey PS, Sarnak MJ.(1998) Epidemiology of cardiovascular disease in chronic renal disease. Journal of the American Society of Nephrology: JASN;9(12 Suppl):S16-23.

Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, et al.(2003) Kidney disease as a risk factor for development of cardiovascular disease a statement from the American Heart Association Councils on kidney in cardiovascular disease, high blood pressure research, clinical cardiology, and epidemiology and prevention. Circulation;108(17):2154-69.

Gum PA, Kottke-Marchant K, Poggio ED, Gurm H, Welsh PA, Brooks L, et al.(2001) Profile and prevalence of aspirin resistance in patients with cardiovascular disease. The American journal of cardiology;88(3):230-5.

Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, et al.(2012) Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation;125(1):e2.

Kivimäki M, Virtanen M, Elovainio M, Kouvonen A, Väänänen A, Vahtera J.(2006) Work stress in the etiology of coronary heart disease—a meta-analysis. Scand J Work Environ Health:431-42.

Bostom AG, Lathrop L.(1997) Hyperhomocysteinemia in end-stage renal disease: prevalence, etiology, and potential relationship to arteriosclerotic outcomes. Kidney Int;52(1):10-20.

Brand‐Miller JC.(2003) Glycemic load and chronic disease. Nutr Rev;61(s5):S49-S55.

Al-Waili NS.(2004) Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucrose. J Med Food;7(1):100-7.

Yaghoobi N, Al-Waili N, Ghayour-Mobarhan M, Parizadeh S, Abasalti Z, Yaghoobi Z, et al.(2008) Natural honey and cardiovascular risk factors; effects on blood glucose, cholesterol, triacylglycerole, CRP, and body weight compared with sucrose. The scientific world journal;8:463-9.

Chepulis L, Starkey N.(2008) The Long‐Term Effects of Feeding Honey Compared with Sucrose and a Sugar‐Free Diet on Weight Gain, Lipid Profiles, and DEXA Measurements in Rats. J Food Sci;73(1):H1-H7.

Bahrami M, Ataie-Jafari A, Hosseini S, Foruzanfar MH, Rahmani M, Pajouhi M.(2009) Effects of natural honey consumption in diabetic patients: an 8-week randomized clinical trial. Int J Food Sci Nutr;60(7):618-26.

Grodstein F, Stampfer M.(1995) The epidemiology of coronary heart disease and estrogen replacement in postmenopausal women. Prog Cardiovasc Dis;38(3):199-210.

Münstedt K, Hoffmann S, Hauenschild A, Bülte M, von Georgi R, Hackethal A.(2009) Effect of honey on serum cholesterol and lipid values. J Med Food;12(3):624-8.

Alagwu E, Okwara J, Nneli R, Osim E.(2011) Effect of honey intake on serum cholesterol, triglycerides and lipoprotein levels in albino rats and potential benefits on risks of coronary heart disease. Niger J Physiol Sci;26(2):161-5.


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